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您的位置: 文学城 » 博客 »cyclosporine is not good for wound healing? Why?

cyclosporine is not good for wound healing? Why?

2023-11-07 13:33:17

TJKCB

TJKCB
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Tjkcb notes: I got a minor cut, searching for the"First Aids" Box, but did not find Cyclosporine A  as I used to use.  I asked and was told that Cyclosporine A keeps the moisture in the wound, prohibiting the wound cells from dying (apopotosis) and allowing fresh skin cells to grow (healing). 

Aha! 

Shocked! schocking to hear "cyclosporine is not good for wound healing"—rushing to check it out below.

What is your conclusion?

** 

Cyclosporine A delays wound healing and apoptosis and suppresses activin beta-A expression in rats. Eur J Dermatol.
 

Cyclosporine A delays wound healing and apoptosis and ...

National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
 
 
 
 
 
 
About featured snippets•
 
Feedback
People also ask
 
 
What drugs cause poor wound healing?
 
 
Medications That Affect Wound Healing

Medications that have been reported to delay wound healing include anticoagulants, antimicrobials, various antibiotic classes, bevacizumab, aflibercept, antineoplastic agents, chemotherapeutics, immunosuppressants, and colchicine.Feb 28, 2022
 

Polypharmacy and Complex Wounds - WoundSource

woundsource.com
https://www.woundsource.com › blog › polypharmacy-a...
 
 
 
Search for: What drugs cause poor wound healing?
 
Do immunosuppressants affect wound healing?
 
 
 
What medications inhibit wound healing?
 
 
 
What are the contraindications for cyclosporine?
 
 
 
What is the best anti-inflammatory for wound healing?
 
 
 
What would cause poor wound healing?
 
 
 
 
Feedback
 

Effect of cyclosporine on wound healing

National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
 
 
 
by A Nemlander · 1983 · Cited by 44 — We conclude that, in contrast to MP, cyclosporine does not inhibit the inflammatory reaction of granulation tissue formation or the regenerative process of ...
 
 

Effect of Cyclosporin A on Wound Healing After Glaucoma ...

IOVS | ARVO Journals
https://iovs.arvojournals.org › article
 
 
 
by YD Kim · 2008 — The cyclosporin A(CsA) is an immunosuppressant that can suppress inflammation and fibroblast proliferation and modulate wound healing process. And it has fewer ...
 
 

Effects of immunosuppressive therapy on wound healing

Wiley Online Library
https://onlinelibrary.wiley.com › doi › pdf
 
 
 
by R Bootun · 2013 · Cited by 125 — Abstract. Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees.
 
 

effect of cyclosporine on wound healing an analysis with ...

Lippincott Williams & Wilkins
https://journals.lww.com › transplantjournal › Citation
 
 
 
The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients.
 
 

Cyclosporin A reduces matrix metalloproteinases and ...

Fibrogenesis & Tissue Repair
https://fibrogenesis.biomedcentral.com › articles
 
 
 
by B Gawronska-Kozak · 2013 · Cited by 24 — Cyclosporin A (CsA), an immunosuppressive agent modifies the wound healing process through an influence on extracellular matrix metabolism.
 
 

Comparison of effects of the tacrolimus and cyclosporine A ...

 
Annals of Surgical Treatment and Research
https://www.astr.or.kr › PDFData › astr-92-402
 
 
 
by E Uysal · 2017 · Cited by 8 — In rats, the adverse effect of cyclosporin A has not been shown on primary wound healing [14]. In another study, anasto- motic complications were less ...
 
 

Effect of cyclosporine on wound healing.

Semantic Scholar
https://www.semanticscholar.org › paper › Effect-of-cycl...
 
 
 
Jul 1, 1983 — It is concluded that cyclosporine does not inhibit the inflammatory reaction of granulation tissue formation or the regenerative process of ...
 
 

The Safety of Elective Surgery with Concurrent Use ...

OAText
https://oatext.com › The-Safety-of-Elective-Surgery-w...
 
 
 
However, the use of cyclosporine is still considered appropriate with special care ... no history of wound healing problems. This result was shown in a small ...
 
 

Topical cyclosporin as a novel treatment for pyoderma ...

 
Journal of the American Academy of Dermatology
https://www.jaad.org › article › abstract
 
 
 
About 1 cc of the medication was applied to the ulcer twice daily followed by the application of a petrolatum impregnated gauze and a light bandage. The ulcer ...
 
 
 
 
People also ask
 
 
What condition causes wounds not to heal?
 
 
Infections. The most common factor that causes non-healing wounds is infection. If a wound becomes infected or contaminated, the body's immune system directs its efforts toward fighting bacteria rather than healing. Bacteria can also cause cell death as well as toxins that can delay or stop healing.Apr 15, 2015
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cyclosporine is not...
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TJKCB

TJKCB

cyclosporine is not good for wound healing? Why?

TJKCB (2023-11-07 13:33:17) 评论 (0)

Tjkcb notes: I got a minor cut, searching for the"First Aids" Box, but did not find Cyclosporine A  as I used to use.  I asked and was told that Cyclosporine A keeps the moisture in the wound, prohibiting the wound cells from dying (apopotosis) and allowing fresh skin cells to grow (healing). 

Aha! 

Shocked! schocking to hear "cyclosporine is not good for wound healing"—rushing to check it out below.

What is your conclusion?

** 

Cyclosporine A delays wound healing and apoptosis and suppresses activin beta-A expression in rats. Eur J Dermatol.
 

Cyclosporine A delays wound healing and apoptosis and ...

National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
 
 
 
 
 
 
About featured snippets•
 
Feedback
People also ask
 
 
What drugs cause poor wound healing?
 
 
Medications That Affect Wound Healing

Medications that have been reported to delay wound healing include anticoagulants, antimicrobials, various antibiotic classes, bevacizumab, aflibercept, antineoplastic agents, chemotherapeutics, immunosuppressants, and colchicine.Feb 28, 2022
 

Polypharmacy and Complex Wounds - WoundSource

woundsource.com
https://www.woundsource.com › blog › polypharmacy-a...
 
 
 
Search for: What drugs cause poor wound healing?
 
Do immunosuppressants affect wound healing?
 
 
 
What medications inhibit wound healing?
 
 
 
What are the contraindications for cyclosporine?
 
 
 
What is the best anti-inflammatory for wound healing?
 
 
 
What would cause poor wound healing?
 
 
 
 
Feedback
 

Effect of cyclosporine on wound healing

National Institutes of Health (.gov)
https://pubmed.ncbi.nlm.nih.gov › ...
 
 
 
by A Nemlander · 1983 · Cited by 44 — We conclude that, in contrast to MP, cyclosporine does not inhibit the inflammatory reaction of granulation tissue formation or the regenerative process of ...
 
 

Effect of Cyclosporin A on Wound Healing After Glaucoma ...

IOVS | ARVO Journals
https://iovs.arvojournals.org › article
 
 
 
by YD Kim · 2008 — The cyclosporin A(CsA) is an immunosuppressant that can suppress inflammation and fibroblast proliferation and modulate wound healing process. And it has fewer ...
 
 

Effects of immunosuppressive therapy on wound healing

Wiley Online Library
https://onlinelibrary.wiley.com › doi › pdf
 
 
 
by R Bootun · 2013 · Cited by 125 — Abstract. Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees.
 
 

effect of cyclosporine on wound healing an analysis with ...

Lippincott Williams & Wilkins
https://journals.lww.com › transplantjournal › Citation
 
 
 
The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients.
 
 

Cyclosporin A reduces matrix metalloproteinases and ...

Fibrogenesis & Tissue Repair
https://fibrogenesis.biomedcentral.com › articles
 
 
 
by B Gawronska-Kozak · 2013 · Cited by 24 — Cyclosporin A (CsA), an immunosuppressive agent modifies the wound healing process through an influence on extracellular matrix metabolism.
 
 

Comparison of effects of the tacrolimus and cyclosporine A ...

 
Annals of Surgical Treatment and Research
https://www.astr.or.kr › PDFData › astr-92-402
 
 
 
by E Uysal · 2017 · Cited by 8 — In rats, the adverse effect of cyclosporin A has not been shown on primary wound healing [14]. In another study, anasto- motic complications were less ...
 
 

Effect of cyclosporine on wound healing.

Semantic Scholar
https://www.semanticscholar.org › paper › Effect-of-cycl...
 
 
 
Jul 1, 1983 — It is concluded that cyclosporine does not inhibit the inflammatory reaction of granulation tissue formation or the regenerative process of ...
 
 

The Safety of Elective Surgery with Concurrent Use ...

OAText
https://oatext.com › The-Safety-of-Elective-Surgery-w...
 
 
 
However, the use of cyclosporine is still considered appropriate with special care ... no history of wound healing problems. This result was shown in a small ...
 
 

Topical cyclosporin as a novel treatment for pyoderma ...

 
Journal of the American Academy of Dermatology
https://www.jaad.org › article › abstract
 
 
 
About 1 cc of the medication was applied to the ulcer twice daily followed by the application of a petrolatum impregnated gauze and a light bandage. The ulcer ...
 
 
 
 
People also ask
 
 
What condition causes wounds not to heal?
 
 
Infections. The most common factor that causes non-healing wounds is infection. If a wound becomes infected or contaminated, the body's immune system directs its efforts toward fighting bacteria rather than healing. Bacteria can also cause cell death as well as toxins that can delay or stop healing.Apr 15, 2015