can you give me details about the company agebox and its main product iKids-Growth, and why FDA gives warning on this drug may contains performance enhancement chemical?
下面是它的回答：
ChatGPT said:
Here’s a detailed summary of what is known so far about AGEBOX (or “Agebox”) and its product iKids-Growth, and why the FDA issued a warning about it.
What is AGEBOX and iKids-Growth
AGEBOX / Agebox
AGEBOX (or Agebox) is described as a U.S.-based biotechnology / nutraceutical company focused on formulations that support children’s growth, cognition, etc.
Morningstar
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Nutraceutical Business Review
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According to a press release, they present “iKids-Growth” as a “safe and natural support for children’s height development.”
Nutraceutical Business Review
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Morningstar
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The company claims that iKids-Growth “syncs with the body’s natural growth signalling system,” meaning they assert it complements natural physiological regulation rather than acting directly as a strong agent.
Nutraceutical Business Review
In their promotional materials, they emphasize that the formulation is “hormone-free.”
Morningstar
iKids-Growth
iKids-Growth is marketed as a supplement (or “nutraceutical”) intended to help children reach their growth / height potential by enhancing the body’s ability to translate nutrition, sleep, and activity into growth.
Nutraceutical Business Review
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Morningstar
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It appears there are sub-formulas or variants (e.g. “Day Formula,” “Night Formula”) under the iKids-Growth brand. The FDA warning specifically references the Day formula.
U.S. Food and Drug Administration
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There is at least one registered clinical trial (in China) purporting to evaluate the “dietary supplement ‘iKids-Growth’ in improving height growth” in a specific patient group (SRS patients aged 1 to 3). (SRS = presumably “Silver-Russell syndrome” or similar growth-disorder context)
Chictr
The company frames iKids-Growth as an “evidence-based dietary supplement,” though whether that evidence is peer-reviewed and robust is uncertain.
Morningstar
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In summary: AGEBOX presents itself as a biotech / nutraceutical company and positions iKids-Growth as a (non-hormonal) growth support supplement for children.
FDA Warning and Hidden Ingredient Concern
In September 2025, the FDA issued a Medication Health Fraud Notification concerning Agebox iKids Growth Day Formula.
U.S. Food and Drug Administration
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The key points:
Undeclared Ibutamoren Detected
FDA’s laboratory analysis found that the product contains ibutamoren, which was not listed on the product label.
U.S. Food and Drug Administration
Ibutamoren (also known as MK-677) is a growth hormone secretagogue (a compound that stimulates the secretion of growth hormone). It is not an approved ingredient for over-the-counter supplements for children in the U.S.
U.S. Food and Drug Administration
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U.S. Food and Drug Administration
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Because it is a pharmacologically active compound with effects on hormone regulation, its presence constitutes a “hidden drug” in the supplement. The FDA considers that serious.
U.S. Food and Drug Administration
Risks / Why FDA is Concerned
The presence of ibutamoren means the product is misbranded: what’s inside differs from what’s claimed on the label.
It may pose safety risks, especially in children, because pharmacologically active hormones or hormone-modulating agents can have unintended consequences (e.g. on endocrine regulation, growth plates, other organs).
The product is being marketed as a “supplement” but in effect acts (or at least contains) a drug-like agent.
Because ibutamoren is not approved in this context and is not disclosed, consumers (or clinicians) cannot evaluate risks appropriately.
Hence, the FDA’s warning: "Agebox iKids Growth Day Formula may be harmful due to hidden ingredient."
U.S. Food and Drug Administration
Additionally, in the FDA’s Health Fraud Product Database, iKids Growth (Day and Night formulas) are listed under “undisclosed ibutamoren.”
U.S. Food and Drug Administration
first, is Agebox an American company or Chinese company?
ChatGPT said:
It is not entirely clear whether Agebox is purely an American company or a Chinese company. The evidence is mixed and appears to suggest a hybrid / “international” setup. Below is a breakdown of what I found, with caveats.
Evidence for “American” / U.S. positioning
U.S. incorporation / address claims
A press release states: “Country & City: Richmond, VA, U.S.” in its corporate contact info.
Yahoo Finance
The “About Agebox” page says the supplement is made in the U.S. and shipped from a U.S. warehouse.
shop.agebox***
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shop.agebox***
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In product marketing, they mention “GMP certified” and compliance with U.S. manufacturing standards.
shop.agebox***
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Regulatory signals and scrutiny in the U.S.
The FDA has issued warnings about iKids-Growth Day / Night formulas as products sold by “Agebox.” The U.S. regulatory focus suggests the product is being marketed into U.S. channels.
U.S. Food and Drug Administration
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Evidence for “Chinese / Chinese-market / Chinese association”
Chinese media / reporting
A Chinese article states: “阿基孚是美国品牌 agebox 旗下的产品 … 2022年底进入中国市场 …” (i.e. “AJifu is a product under the U.S. brand Agebox … entered the Chinese market at end of 2022 …”)
36Kr
Other Chinese media refer to “agebox 阿基孚” (iKids-Growth) and discuss it heavily in the Chinese market, suggesting localized operations or targeting in China.
cb***ibaowang******
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Sina News
+3
Sohu
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Trademark / company registration hints
Some commentary claims that Agebox is owned by “AGEBOX LIMITED” registered in Hong Kong (“安基葆国际有限公司（AGEBOX LIMITED）注册于中国香港”) based on trademark or business database sources. However, those are not authoritative corporate filings in and of themselves.
Wenxue City
The Chinese clinical trial registration (for iKids-Growth) lists an applicant address in Hangzhou, China for the trial study. This does not prove company ownership, but shows the product is being studied / registered via Chinese institutions.
Chictr
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Media skepticism / criticisms
Some Chinese media say explicitly: “检索发现这是一家美国公司生产的膳食补充剂，而且和中国似乎有很多关联，包括研发销售等。” — “It was found that this is a dietary supplement produced by a U.S. company, but has many connections with China including R&D, sales, etc.”
Tencent News
Some local / internet commentary claims the company headquarters or brand registration is in Hong Kong.
Wenxue City
My Best Assessment
Given the evidence:
Agebox appears to position itself as a U.S.-based company (or at least a company that does manufacturing / warehouses / legal presence in the U.S.).
However, it also has strong ties to China / Chinese markets, including local branding (“阿基孚”), Chinese marketing, and possibly local registration or brand ownership structures in Hong Kong / China.
So it is plausible that Agebox is structured as a cross-border / international company—perhaps a U.S.-incorporated entity with operations, marketing, or affiliate arms in China / Hong Kong.
If you like, I can try to find its corporate registration documents (in the U.S. or Hong Kong) to see definitively where it's legally domiciled. Would you like me to do that?
"We don't guess. We test," says Dr. Simon Liu, Head of Scientific Development at AGEBOX.
"Our goal was to create something parents could genuinely trust, not just because it's clean, but because every ingredient serves a real biological purpose," says Ryan Lawson, AGEBOX's Chief Brand Officer.
Media Contact
Company Name: AGEBOX Inc.
Contact Person: Catalina Chan
总有王里 发表评论于 2025-09-26 13:47:34
大概率是老中骗老中。Made in U.S.A. by 老中for老中
有意义的标题应该是“中方检出兴奋剂物质近一年后，美方FDA认可”
