长链mRNA本身就是抗原,不管它的mRNA序列是否是新冠病毒的SPIKE蛋白的还是全部都是single strand poly A。均可以通过TOLL-like receptor激活非特异性免疫反应。mRNA疫苗产生了主要副作用 (参阅文献Adverse events following COVID‐19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia, Immun Inflamm Dis. 2023 Mar; 11(3): e807. Published online 2023 Mar 17. doi: 10.1002/iid3.807)和单链RNA在动物体内激活产生的炎性因子IL-1b, iNOS所导致的现象很相近。懂病毒和免疫学的人都知道。这也是为什么很多医生不愿打mRNA疫苗。那就是一笔糊涂账,产生的那点免疫反应是应激反应,非特异不持久,如个体敏感,产生的副作用会非常严重。A total of 81 articles analyzed confirmed cardiovascular complications post‐COVID‐19 mRNA vaccines in 17,636 individuals and reported 284 deaths with any mRNA vaccine. Of 17,636 cardiovascular events with any mRNA vaccine, 17,192 were observed with the BNT162b2 (Pfizer−BioNTech) vaccine, 444 events with mRNA‐1273 (Moderna). Thrombosis was frequently reported with any mRNA vaccine (n = 13,936), followed by stroke (n = 758), myocarditis (n = 511), myocardial infarction (n = 377), pulmonary embolism (n = 301), and arrhythmia (n = 254). Stratifying the results by vaccine type showed that thrombosis (80.8%) was common in the BNT162b2 cohort, while stroke (39.9%) was common with mRNA‐1273 for any dose. The time between the vaccination dosage and the first symptom onset averaged 5.6 and 4.8 days with the mRNA‐1273 vaccine and BNT162b2, respectively. The mRNA‐1273 cohort reported 56 deaths compared to the 228 with BNT162b2, while the rest were discharged or transferred to the ICU.