美癌症患者确诊471天破纪录!病毒还在体内"变异3次"
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美国康乃狄克州一名癌症病患在2020年11月确诊新冠肺炎,结果超过471天后检测结果仍是阳性,而在这段时间里,他体内病毒载量非常高,且同样具有传染性。研究人员更发现,新冠病毒至少进化出3种不同的变异株。
美国耶鲁大学和北卡罗莱纳州、澳洲的研究团队合作,在康乃狄克州追踪变种病毒时,竟意外发现一名60多岁的淋巴瘤病患身上,居然有消失已久的B.1.517谱系病毒。进一步研究后发现,这名癌症病患在2020年11月确诊后,直到今年3月的检测结果都还是阳性,代表他已染疫超过471天。
研究人员指出,患者刚确诊时仅前几天有轻微症状,不过在长达471天的确诊时间中,他仍具有传染性,而且体内病毒载量非常高。此外,随着时间增加,病毒居然在他体内迅速进化,出现三个不同的新病毒谱系,研究人员表示,「这证明慢性感染可能会加速新冠病毒进化与分化,这一机制可能会帮助病毒出现基因多样化的变种,包含Omicron、Delta和Alpha。」
研究结果指出,病毒在免疫功能低下病患体内的变异速度,可能是普通人的两倍,同时强调了免疫功能低下病患成为新冠病毒变异宿主的可能性;先前也有南非科学家指出,Omicron病毒可能来自于一名慢性病患者。
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