Plants, animals, and humans adapt their biological rhythm with the Earth's revolutions, this way they can all stay synchronized.
Scientists knew these centuries before they understood what made
them tick. Three American scientists, Jeffrey C Hall, Michael Rosbash and Michael W Young, have been dedicated their research
for insights into the internal biological clock. They
identified a gene within fruit flies responsible for
controlling the daily rhythm, known as period gene.
The transcription level of this
gene oscillates with the rotation of our planet. The research
won them the 2017 Nobel Prize in Physiology/ Medicine.
The internal clock is a key feature of life on Earth, one that
wired the rotation of the planet into the fabric of our cells
over millions of years of evolution.
ScienCell's GeneQuery™ Human Circadian Rhythm qPCR Array Kit
(GQH-CIR) profiles 88 key genes involved in regulating changes that occur on a roughly 24-hour cycle.
Why use GeneQuery™ arrays?
* Genes are selected based on extensive literature research by
our Ph.D. scientist team
* All known transcript variants of target gene are recognized
* Primers are verified with over 10 types of normal human
primary cells to assure universal specificity and biological
relevance
* Performance guaranteed with high efficiency and
reproducibility; free of non-specific amplification
* Customizable with no extra charge
* Individual primers available
Example applications:
Basic research
* Identify cell signaling aberrancies
* Determine relevancy of biological pathways
* Study gene expression manipulation
* Examine mechanisms that may characterize phenotypes
* Compare cell functionality and biology in various conditions
* Confirm clustered RNA-Sequencing, microarrays and other preliminary data
Translational research
* Evaluate novel target genes or markers in discovery biology
* Determine drug mechanism of action in drug screening
* Evaluate new drug performance and enhance development